Dopaminergic antagonists inhibit bile chemotaxis of adult Clonorchis sinensis and its egg production (original) (raw)
Fig 5
Effects of clinical antipsychotic drugs on chemotaxis of CsAds to cholic acid.
The CsAds were stimulated with 100 mM CA solution containing chlorpromazine (A), haloperidol (B), or clozapine (C). The migration distance of the CsAds was measured every 10 min for 2 h. Each drug at 100 mM (except clozapine at 100 μM) was tested for chemo-attractive or chemo-repellent properties (blue triangle up). Asterisks indicate ** p < 0.01 and *** p < 0.001 compared to the CA-only group (red square) at 120 min.