Extracellular Sulfatases, Elements of the Wnt Signaling Pathway, Positively Regulate Growth and Tumorigenicity of Human Pancreatic Cancer Cells (original) (raw)
Figure 2
Autocrine Wnt signaling in pancreatic adenocarcinoma cell lines.
The indicated pancreatic adenocarcinoma cell lines were transfected with sFRP-2 cDNA (sFRP-2) or control vector (ctrl) and the TOP/FOPflash reporter system. Wnt activity was determined by luciferase activity. The values shown are the means±SD's for 3 independent determinations. Differences between sFRP and control were significant in the Student t-test with p values of<0.002 for BxPC-3, HS766T and L3.6sl.