Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling (original) (raw)
Figure 3
Heat map of DNA methylation profiling of identified clones by MCA-RDA.
The bottom red-scale bar refers to the degree of methylation as measured by COBRA and/or pyrosequencing. NL represents normal leukocyte. A. All of the 17 genes investigated were methylated in at least 2 cell lines of a 21-cell line panel investigated. B. Methylation map for 8 genes studied in twenty primary prostate cancers (T) and paired normal (N) prostate samples. C. Methylation map for 9 genes studied in twenty primary colon cancers (T) and paired normal (N) colon samples. D. Methylation map of 7 genes in twenty-four breast cancers (T) and paired normal (N) samples. Pat.; patient samples.