Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis (original) (raw)
Figure 6
The mRNA expression profile of canonical Wnt signaling components in primary human ATII cells.
Primary human ATII cells were isolated from lung tissues of donor and IPF patients as described in Material and Methods. The mRNA levels of Wnt1, 3a, 7b, and 10b (a), the receptors Fzd2 and 3, and Lrp5 and 6 (b), and Gsk-3β, β-catenin, and Lef1 (c) in ATII cells were assessed by qRT-PCR. Results are derived from 3 different cell isolations each and presented as mean±s.e.m., * p<0.05.