A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity (original) (raw)
Figure 7
Adipose tissue JNK activity in JNK1-deficient chimeras.
Total adipose tissue JNK kinase activity (A) and insulin-stimulated insulin receptor phosphorylation (B) were examined in JNK1-deficient mice transplanted with WT or Jnk1−/− bone marrow. Lower graph in panel B shows the quantification of insulin receptor phosphorylation normalized for insulin receptor protein levels. In the JNK kinase assay, the density of each lane is also shown numerically. Asterisk indicates statistical significance (p<0.05) in Student's t test.