Identification of Nuclear and Cytoplasmic mRNA Targets for the Shuttling Protein SF2/ASF (original) (raw)
Figure 2
Distribution of SF2/ASF binding sites in relation to gene structure and sub-cellular localization.
A) The “coding” SF2/ASF CLIP tags from nuclear, cytoplasmic and polysomal sets were analyzed in relation to their relative position within genes. This showed that the majority map to intronic or to coding exonic sequences and only a small proportion mapped to UTRs. B) Venn diagram of exonic SF2/ASF binding sites from Nuclear, cytoplasmic and polysomal sub-cellular fractions. The number of unique binding sites identified in each fraction is designated as “n”.