PhoP: A Missing Piece in the Intricate Puzzle of Mycobacterium tuberculosis Virulence (original) (raw)
Figure 2
Protein expression patterns of M. tuberculosis and the phoP mutant.
Areas of 2D-polyacrylamide gels show differences in the protein expression patterns between the wild type strain and the phoP mutant. Spots that showed at least three-fold differential expression across triplicate gels were selected for identification by mass spectrometry. EspB and Hsp65 are more expressed in the wild type strain while ICL shows a higher expression in the phoP mutant. The vertical arrows indicate decreased (↓) or increased (↑) expression in the M. tuberculosis phoP mutant relative to the parent strain.