Evidence for Co-Evolution between Human MicroRNAs and Alu-Repeats (original) (raw)
Figure 5
Orientation of SINE and LINE repeats in C19MC is not balanced over plus and minus strands.
The analysis is based on the human genome, 1250 random windows of 100 k lengths are shown (total sequence length corresponds to ∼2× length of Chr19). For each window the proportion of SINE (A) and LINE (B) elements is computed with respect to the total integration for that window (blue rhombus; 0 equals 100% of integration on the plus Strand; 1 equals 100% of integration on the minus Strand). Proportions are plotted in regard to their number of total repeat integrations of the corresponding class per window in ascending order from left to right. Red dot: proportion of the miRNA cluster on Chr19 (C19MC), blue dots: random windows.