Rapid Regulatory T-Cell Response Prevents Cytokine Storm in CD28 Superagonist Treated Mice (original) (raw)
Figure 4
Treg depletion results in systemic cytokine release after CD28SA stimulation.
Mice were pretreated with DT to remove Treg cells from DEREG mice as given in Methods, and stimulated with CD28SA for the times indicated. Cytokine levels in peripheral blood are shown.