MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis (original) (raw)
Figure 3
Negative Correlation Between Plasma Levels of miR-150 and Cytokines.
(A) The complementary sequence between miR-150 and the mRNAs of TNF-alpha, IL-10, and IL-18 is shown. Complementary sequences are reported, as well as the relative folding energy between miR-150 and mRNAs by using RNA22. (B) ELISA determination for plasma markers of sepsis and correlation with miR-150 expression in plasma are depicted in the graphs. The left panels show IL-10, IL-18 and TNF-alpha measurements by ELISA in plasma, mean Ct +/− standard deviation have been reported. The right panels show the negative correlation between miR-150 and IL-10, IL-18 and TNF-alpha, respectively. Values, on a patient by patient basis, have been reported for each cytokine studied.