Genomic Diversity among Drug Sensitive and Multidrug Resistant Isolates of Mycobacterium tuberculosis with Identical DNA Fingerprints (original) (raw)
Figure 3
Genomic deletion specific for K-1.
A, Graph showing the depth of coverage. A drop in coverage is visible in K-1 suggesting a deletion relative to the H37Rv reference. B, PCR and subsequent dideoxy sequencing (data not shown) identified a K-1 specific deletion at 859244-859501 (257 bp) affecting cyp123 (Rv0766c) in correspondence with the coverage plot (Figure 3A).