A New Paradigm for MAPK: Structural Interactions of hERK1 with Mitochondria in HeLa Cells (original) (raw)

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Figure 2

hERK1-GST pulldown assay. GST-hERK1 or GST-null recombinant proteins immobilized on GSH-agarose were incubated overnight with a mitochondrial extract.

Beads were extensively washed and eluted proteins were run on SDS-PAGE. Proteins were stained with Coomasie Brilliant Blue G-250. Molecular weight markers displayed on the left. GST-hERK1 and GST-null recombinant proteins highlighted on the right. Numbers on the right side of the bands recovered in GST-hERK lane represent proteins identified by mass spectrometry and shown in Table 1.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0007541.g002