Japanese Encephalitis Virus Induce Immuno-Competency in Neural Stem/Progenitor Cells (original) (raw)
Figure 3
Production of inflammatory cytokines by NSPCs upon JEV infection.
Control and JEV infected neurospheres were collected at 1–4 dpi and cell lysates were prepared. CBA was performed with the cell lysates and the graphs represent the concentration of the different cytokines produced. Significant production of TNF-α (A), IFN-γ (B), IL-6 (C), and CCL2/MCP-1 (D) was observed in JEV infected NSPCs compared to control NSPCs, and the levels of all cyto/chemokines reached the maximum at 3 dpi and 4 dpi. Values represent the means ± SEM from three independent experiments. * indicates p<0.005 compared to control.