Genome-Wide Identification of Schistosoma japonicum MicroRNAs Using a Deep-Sequencing Approach (original) (raw)
Figure 5
Evolutionary analysis of S. japonicum miRNAs.
(A) 21 S. japonicum miRNAs are orthologs of known miRNAs from other bilaterian animals. “+” indicates the high homology with the orthologs of the indicated species or phylum of animals, while “−” indicates no homology with to the orthologs. (B) Alignment of miR-8 homologues from some bilaterian animals. The nucleotides in red represent substitution that is specific to schistosomes, while blue letters indicate nucleotide substitutions found in orthologs or their paralogs in some other species and black letters represent the conserved nucleotides. Abbreviations: sja, S. japonicum; sma, S. mansoni; sme, S. mediterranea; dme, D. melanogaster; dre, D. rerio; fru, F. rubripes; gga, G. gallus; hsa, H. sapiens; mmu, M. musculus; xla, X. laevis; cel, C. elegans; csa, C. savignyi; cin, C. intestinalis; oan, O. anatinus; xtr, X. tropicalis.