Exome Sequencing of a Multigenerational Human Pedigree (original) (raw)

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Figure 2

Sequence coverage of targeted exons.

The graph illustrates the cumulative coverage of targeted bases after sequencing 0.5 Gbp (red), 1 Gbp (blue), 1.5 Gbp (green), and 2 Gbp (purple). 1 Gb resulted in nearly 10x coverage of 50% of all targets; 2 Gb of data increase this number to 88%. Depending on a studies goal, maximum coverage might not always be required.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0008232.g002