Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges (original) (raw)
Figure 4
The objective of the gene expression prediction challenge was to predict temporal expression of 50 genes that were withheld from a training set consisting of 9285 genes.
(a) Clustered heatmaps of the predicted genes (columns) reveal that two best-performer teams predicted substantially similar gene expression values, though different methods were employed. Results for the 60 minute time-point are shown. (b) The benefits of combining the predictions of multiple teams into a consensus prediction are illustrated by the rank sum prediction (triangles). Some rank sum predictions score higher than the best-performer, depending on the teams that are included. The highest score is achieved by a combination of the predictions of the best four teams.