Alterations in Adenosine Metabolism and Signaling in Patients with Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis (original) (raw)

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Figure 2

Lung histopathology and high-resolution CT scans.

Representative H&E staining and hign-resolution CT scan images showing: (A) A Stage 0 COPD patient with preserved lung function. (B) A Mild IPF patient with preserved lung function. (C) A Stage 4 COPD patient. (D) A Severe IPF patient. Sections are representative of 10–14 different patients from each group. The yellow boxes in the CT scan images represent the approximate location of the surgical biopsies for obtaining tissues sections frozen material for analysis in these examples.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0009224.g002