The C. elegans D2-Like Dopamine Receptor DOP-3 Decreases Behavioral Sensitivity to the Olfactory Stimulus 1-Octanol (original) (raw)
Figure 2
DOP-1 does not antagonize DOP-3 in octanol avoidance.
Previous studies showed that DOP-1 can antagonize DOP-3 in cholinergic motor neurons [25]. However, loss of DOP-1 function had no effect on the avoidance of 100% octanol when examined in combination with loss of DOP-3 function. The “on food” response of rgs-3;dop-3 animals was indistinguishable from that of rgs-3;dop-1dop-3 (p>0.5). Alleles used: rgs-3(vs19), dop-1(vs100) and dop-3(vs106). WT = the N2 wild-type strain. The time to respond is shown. n≥40. Error bars represent the standard error of the mean (SEM).