Serum Amyloid P Therapeutically Attenuates Murine Bleomycin-Induced Pulmonary Fibrosis via Its Effects on Macrophages (original) (raw)
Figure 2
Enhanced M2 monocyte/macrophage phenotype in IPF/UIP.
(A–D) Levels of macrophage-associated mediators measured in lung tissue biopsies taken from IPF/UIP patients (filled bars) or from the normal margins of lung tumors following resection (open bars). M2 macrophage-associated IL13 (A), IL1RA (B) and resistin (C); and M1-associated fractalkine/CX3CL1 (D) from non-fibrotic (n = 11) or IPF/UIP (n = 13) lung tissue were assessed using Luminex technology. *_P_≤0.05 significance using Mann Whitney analysis.