Tumor Tissue-Derived Formaldehyde and Acidic Microenvironment Synergistically Induce Bone Cancer Pain (original) (raw)
Figure 1
Formaldehyde concentration in the cultured cancer cell lines in vitro and in vivo.
(A) MRMT-1 cancer cells. (B) Human H1299 lung cancer cells. (C) Human SY5Y cancer cells. (D) Ascites from peritoneal inoculation of Walker 256 mammary gland carcinoma cells. (E) Bone morrow of MRMT-1 breast cancer pain model rat in vivo. (F) Tumor tissues from lung and beast cancer patients. * _p<_0.05, ** _p<_0.01, compared with that of the first day.