Mitochondrial Superoxide Contributes to Blood Flow and Axonal Transport Deficits in the Tg2576 Mouse Model of Alzheimer's Disease (original) (raw)
Figure 1
SOD-2 overexpression improves the regional cerebral blood flow (rCBF) deficits displayed in Tg2576 mice.
A) The graph represents the regional cerebral blood flow (rCBF) levels in 12 to 16 months old WT, SOD-2, Tg2576 and Tg2576/SOD-2 mice as measured by MRI (ASL). Significance was assessed by a one-way ANOVA with Dunnett's post-test for multiple comparisons. ** p<0.01.