Pathway Signature and Cellular Differentiation in Clear Cell Renal Cell Carcinoma (original) (raw)
Figure 6
Osteogenic differentation in clear cell renal cell carcinoma.
a. Cellular differentiation experiments showing that KIJ-308 and KIJ-265 ccRCC cells are capable of osteogenic differentiation in osteogenic media by developing calcium deposits, as shown by Alizarin Red stain. Normal patient-matched cells were unable to differentiate. b. A498 ccRCC cells are also capable of osteogenic differentiation, as shown by Alizarin Red stain, unlike normal renal canine MDCK cells.