Phage-Derived Fully Human Monoclonal Antibody Fragments to Human Vascular Endothelial Growth Factor-C Block Its Interaction with VEGF Receptor-2 and 3 (original) (raw)
Figure 1
Amino acid sequences of ΔNΔC-VEGF-C and ΔNΔC-VEGF-D variants used in the study.
The region of 100% identity within used ΔNΔC-VEGF-C variants is shown within the black frame, the possible epitope regions of VC2.2.2 anti-VEGF-C scFv on ΔNΔC-VEGF-C and the corresponding regions on ΔNΔC-VEGF-D are shown within grey frames. P.p, _P. pastoris_-derived ΔNΔC-VEGF-C; R&D, commercially available mammalian cell-derived ΔNΔC-VEGF-C or ΔNΔC-VEGF-D, respectively.