Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK (original) (raw)

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Figure 2

Stress fiber stretch amplitude depends on stretch frequency.

The relative fiber stretch amplitude α* was estimated by solving the model for the initial cycle of 10% cyclic uniaxial or equibiaxial stretch for frequencies ranging from 0.01 to 10 Hz. The simulations predict that the stress fibers behave elastically above a saturation frequency of ∼1Hz and that the value of α* decreases exponentially as frequency decreases below the saturation frequency.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0012470.g002