Toll-Like Receptor 2 Signaling Protects Mice from Tumor Development in a Mouse Model of Colitis-Induced Cancer (original) (raw)
Figure 2
TLR2-deficient colons have more advanced dysplasia and ß-catenin expression compared to WT colons.
Histopathology of colons at day 61 of AOM-DSS treatment. (A) Hematoxylin and eosin (H&E) (left) or BrdU stained (right) serial sections of WT or TLR2−/− mice are shown. Original magnification 20x (upper panels) and 100x (lower panels) are shown. (B) Immunofluorescent staining for ß-catenin. Original magnification 100x (left panel) or 400x (right panel).