The Dopamine Metabolite 3-Methoxytyramine Is a Neuromodulator (original) (raw)
Figure 4
Striatal signaling effects of 3-MT are reduced in TAAR1-KO mice.
Effect of 3-MT infusion (18 µg, 30 min after treatment) on Erk2 (A) and CREB (B) phosphorylation in WT and TAAR1-KO mice. 3-MT induced significant phosphorylation of both Erk2 and CREB in WT mice, but not in TAAR1-KO mice (* p<0.05; Student's t-test n = 10 per group).