White Matter Changes and Word Finding Failures with Increasing Age (original) (raw)
Figure 2
Fractional Anisotropy by age and hemisphere: a) Age-related reductions in FA are shown superimposed on a T1-weighted spatially normalized brain scan.
Left side of the axial slices corresponds to left hemisphere. Color bar indicates range of t-scores. b) FA values obtained from all participants are shown plotted as a function of age. Mean FA values were obtained from 10 mm diameter spheres centered at the peaks of the three most significant voxels resulting from the whole brain SPM analysis. (i) −36 −35 −1 (r = −.87, p<.001), (ii) −47 −45 31 (r = −.83, p<.001) (iii) −2 6 −1 (r = −.86, p<.001). c) Cross-hemispheric FA comparisons are shown superimposed on a T1-weighted spatially normalized brain scan. Color bar indicates range of t-scores, with higher values reflecting greater asymmetry.