Predicting Pancreas Cell Fate Decisions and Reprogramming with a Hierarchical Multi-Attractor Model (original) (raw)
Figure 6
The gene expression profiles of knock out simulations.
(A) The case of knocking out Pax4: α cell marker Brn4 is expressed while no MafA and δ cell gene are expressed; (B) The case of knocking out Arx: MafA and δ cell gene are expressed while Brn4 is not expressed.