CD4+CD25+Foxp3+ Regulatory T Cells Depletion May Attenuate the Development of Silica-Induced Lung Fibrosis in Mice (original) (raw)
Figure 6
The expression of CTLA-4 in Treg cells in the HLN and spleen.
CTLA4 expressed in CD4+CD25+FOXP3+ Treg cells of HLN (A) and spleen (C) was assayed by flow cytometry. (n = 5) The number of Treg cells expressing CTLA4 of HLN (B) and spleen (D) was shown in the graph. (n = 5) (*, as compare with the saline control group, P<0.05; △, as compare with the silica group, P<0.05; #, as compare with 7day of the same group, P<0.05; &, as compare with 28day of the same group, P<0.05).