PPARδ Activation Acts Cooperatively with 3-Phosphoinositide-Dependent Protein Kinase-1 to Enhance Mammary Tumorigenesis (original) (raw)
Figure 4
The metabolome of GW501516-treated wild-type and MMTV-PDK1 mice.
Wild-type (WT) and MMTV-PDK1 (PDK1) mice were maintained for 7 days on either standard or GW501516 (GW)-supplemented diets. The metabolite levels in mammary gland extracts were analyzed by UPLC-ESI-TOFMS. The heatmaps depict the changes in negative ions for control and GW-treated WT and PDK1 mice in 6 replicate analyses.