MicroRNAs Differentially Expressed in Postnatal Aortic Development Downregulate Elastin via 3′ UTR and Coding-Sequence Binding Sites (original) (raw)
Figure 5
miRNAs targeting coding sequence MREs can reduce the expression level of ECM genes in RFL-6 cell culture.
Triplicate qPCR analyses for Col1a1, Col1a2, and Eln following treatment of RFL-6 cells with scrambled (black), miR-29 (dark grey), or miR-195 (light grey) precursor. Data are presented as mean SEM for three independent treatments (
,
,
).