The Mechanism of Excessive Intestinal Inflammation in Necrotizing Enterocolitis: An Immature Innate Immune Response (original) (raw)
Figure 5
RNAi knockdown of A-20 and TOLLIP in fetal enterocytes followed by PAM3Cys (TLR2 ligand) stimulus.
(A) The IL-8 cytokine level after knockdown increased to that shown in NEC enterocytes. The representative efficiency of (B) A-20 knockdown of mRNA and (C) protein was appropriate for the altered observation as compared to a control level of one. (*p<0.01; ** p<0.001).