Exploring Metabolic Pathway Reconstruction and Genome-Wide Expression Profiling in Lactobacillus reuteri to Define Functional Probiotic Features (original) (raw)
Figure 1
(Poly)saccharide metabolism in L. reuteri ATCC 55730 and ATCC PTA 6475.
Metabolic reactions present in both strains are highlighted in dark grey. Metabolic reactions only present in L. reuteri ATCC 55730 are highlighted in black. Abbreviations are indicated for reactions present at least in one strain. [e]: extracellular; 6pgg: 6-phospho-beta-D-glucosyl-(1,4)-D-glucose; acgal6p: N-acetylgalactosamine 6-phosphate; acgala: N-Acetyl-D-galactosamine; ACGALpts: N-acetylgalactosamine PTS; a-gal-D: alpha-D galactose; CELBpts: cellobiose transport via PEP:Pyr PTS; cellb: cellobiose; CPS_LPL2: capsular polysaccharide linkage unit, LPL specific; CPSS_LPL2: CPS synthase complex, LPL specific; dtdp6dm: dTDP-6-deoxy-L-mannose; dtdpddg: dTDP-4-dehydro-6-deoxy-D-glucose; dtdpddm: dTDP-4-dehydro-6-deoxy-L-mannose; dtdpglc: dTDPglucose; dttp: dTTP; f6p: D-Fructose 6-phosphate; fru: D-Fructose; FRUK: fructokinase; g1p: D-Glucose 1-phosphate; G1PTMT: glucose-1-phosphate thymidylyltransferase; g6p: D-glucose 6-phosphate; g6p-B: beta-D-glucose 6-phosphate; G6P: Glucose-6-phosphate isomerase; gal: D-galactose; gal1p: alpha-D-Galactose 1-phosphate: GALK2: galactokinase; GALM: aldose 1-epimerase; GALS3: a-galactosidase (melibiose); GALSZ: beta-galactosidase; GALT: galactose-1-phosphate uridylyltransferase; GALU: UTP-glucose-1-phosphate uridylyltransferase; glc-D: D-glucose; lcts: lactose; LCTSt6: lactose transport in/out via proton symport; MALP: maltose phosphorylase; malt: maltose; MALT: alpha-glucosidase; man: D-mannose; man1p: D-mannose 1-phosphate; man6p: D-mannose 6-phosphate; MAN6PI: mannose-6-phosphate isomerase; MANpts: D-mannose transport via PEP:Pyr PTS; melib: melibiose; PGGH: 6-phospho-beta-glucosidase; PGI: glucose-6-phosphate isomerase; PGMT: phosphoglucomutase; PGMT_B: b-phosphoglucomutase; PMANM: phosphomannomutase; raffin: raffinose; RAFGH; raffinose galactohydrolase; suc6p: sucrose 6-phosphate: SUCpts: sucrose transport via PEP:Pyr PTS; sucr: sucrose; TDPDRE: dTDP-4-dehydrorhamnose 3,5-epimerase; TDPDRR: dTDP-4-dehydrorhamnose reductase; TDPGDH: dTDPglucose 4,6-dehydratase; tre: trehalose; tre6p: alpha'-trehalose 6-phosphate; TREpts: trehalose transport via PEP:Pyr PTS; udpg; UDPglucose; UDPG4E: UDPglucose 4-epimerase; udpgal: UDPgalactose. The red boxes depict compound that can be incorporated in biomass.