DNA Methyltransferase Controls Stem Cell Aging by Regulating BMI1 and EZH2 through MicroRNAs (original) (raw)
Figure 5
DNMT inhibition decreased PcG expression.
(a) EZH2 and BMI1 expression levels were investigated by real-time qPCR (left) and western blot (right) in early and late passages of hUCB-MSCs. (b) EZH2 and BMI1 expression levels were investigated by real-time qPCR (left) and western blot (right) after the indicated duration treatment of 5-AzaC. (c) Expression levels of BMI1 and EZH2 were investigated by real-time qPCR after DNMT1 and DNMT3B inhibition.