Serological Evidence of Discrete Spatial Clusters of Plasmodium falciparum Parasites (original) (raw)
Figure 3
Scatter plots of anti-PfEMP1 domain specific sero-clusters are shown by homestead residence in Kilifi only (longitude vs latitude).
The mean responses and 95% confidence intervals inside and outside the hotspot are shown on a log scale to the left of each scatter plot. Red or green shading shows location inside or outside the hotspot, respectively. For example, domain number 1 (top left panel) is from a group A PfEMP1 (1, orange), is a CIDR domain (2, blue), and shows statistically significant clustering at the p = 0.001 level (3, red), antibody responses within the cluster are well above the 95% CI for responses outside (boxed plot of two points with confidence intervals), and on an aerial view the hotspot is in the North-east of the study area (indicated by the red spots).