High-Resolution Description of Antibody Heavy-Chain Repertoires in Humans (original) (raw)

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Figure 3

V, D, and J segment use in mouse is also highly uneven.

Lines indicate cumulative distributions (measured on right-hand side y-axis) (a)–(c). Out of space considerations only V segments present at ≥1% are shown. Insets show cumulative distributions. VDJ combinations also appear unevenly, with the ∼200 most frequent VDJ combinations responsible for 50 percent of all recombination events (d).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0022365.g003