Correlations among Brain Gray Matter Volumes, Age, Gender, and Hemisphere in Healthy Individuals (original) (raw)

< Back to Article

Figure 9

Correlations between age group and regional gray matter volumes in the superior frontal gyrus (A), precentral gyrus (B), superior parietal lobule (C), postcentral gyrus (D), supramarginal gyrus (E), inferior parietal lobule (F), middle frontal gyrus (G), paracentral lobule (H), angular gyrus (I), superior temporal gyrus (J), middle occipital gyrus (K), inferior frontal gyrus (L), middle temporal gyrus (M), inferior occipital gyrus (N), left inferior temporal gyrus (O), right inferior temporal gyrus (P), anterior lobe of the cerebellum (Q), and posterior lobe of the cerebellum (R).

Graphs of both the left and right hemispheres of the inferior temporal gyrus are shown because of the age × gender × hemisphere interaction in the region. In each graph, the vertical axis indicates regional gray matter volume (no units), and the horizontal axis refers to subjects in the third (aged 20–29), fourth (aged 30–39), fifth (aged 40–49), sixth (aged 50–59), and seventh (aged 60–69) decades of life, respectively, moving from left to right. Blue and red lines indicate data obtained from men and women, respectively. To facilitate comparisons of the rate of gray matter volume decline in each region, the range of the vertical axis was set at 0.15, with the exception of the left and right inferior temporal gyri (in which the range was set at 0.20). Each graph is superimposed onto a brain MR image of the lateral view that nearly corresponds to the anatomical location. Asterisk in each graph indicates a region that shows significant age by gender interactions.

Figure 9

doi: https://doi.org/10.1371/journal.pone.0022734.g009