LPS-Induced Galectin-3 Oligomerization Results in Enhancement of Neutrophil Activation (original) (raw)
Figure 7
Gal 3/LPS interaction decreases mice resistance to the lethality of LPS.
A: Groups of 5 Balb/C mice were challenged with PBS, 6.2, 12.5 or 25 mg/kg of E. coli LPS by intraperitoneal (ip) injection. B: Mice (5 per group) were challenged with 500 µl of PBS, Gal 3 (40 µM), 6.2 mg/kg LPS or with a mixture of LPS (6.2 mg/kg) and Gal 3 (40 µM) preincubated for 15 min. The mortality rate was monitored regularly and represented as percentage of survival. *p<0.05.