Mll5 Is Required for Normal Spermatogenesis (original) (raw)
Figure 4
Terminal spermatogenesis is impaired in homozygous Mll5tm1Apa mice.
Morphology of spermatozoa in the seminiferous tubules of testes from wild type (A–B) and Mll5 tm1Apa homozygous males (C–D). In all sections, the lumen is marked by an asterisk (*). Electron micrographs showing the head regions of spermatozoa for comparison, with the letters ‘a’ labelling the acrosome cap and ‘Nu’, the nucleus containing condensed chromatin, respectively. Regions of differences in the mutant from the wild type are indicated by ‘!’. The scale bars represent 0.5 µm (A, C) and 0.2 µm (B, D), respectively.