Radiation–Induced Signaling Results in Mitochondrial Impairment in Mouse Heart at 4 Weeks after Exposure to X-Rays (original) (raw)
Figure 2
Graphical representation of the top protein interaction network of differentially regulated proteins.
All deregulated proteins (0.2 Gy and 2 Gy ICPL and 2D-DIGE; Tables 1, 2 and 3) were imported into the Ingenuity Pathway Analysis as described in Material and Methods. The proteins marked in red represent the upregulated proteins and in green the downregulated proteins. The complex III proteins formed a clearly defined cluster of functionally related proteins. The solid arrows represent direct interactions and the dotted arrows indirect interactions.