Serum MicroRNAs as Biomarkers for Hepatocellular Carcinoma in Chinese Patients with Chronic Hepatitis B Virus Infection (original) (raw)
Figure 1
Expression levels of miRNAs in serum of HCC patients and healthy subjects.
Levels of miR-122 (A), miR-222 (B), miR-223 (C), miR-21 (D), miR-221 (E), and miR-301 (F) were measured in serum of HCC patients (n = 10) and healthy subjects (n = 10) by RT-qPCR. Using miR-16 as normalization control, 3 significantly up-regulated miRNAs (miR-122, miR-222 and miR-223) and 1 significantly down-regulated miRNA (miR-21) in serum in HCC patients were identified, while expression levels of miR-221 and miR-301 in serum were non-significantly higher in HCC patients than in healthy subjects.