Asiatic Acid Inhibits Liver Fibrosis by Blocking TGF-beta/Smad Signaling In Vivo and In Vitro (original) (raw)
Figure 9
AA induces Smad7 expression by HSC-T6 cells in a time and dosage-dependent manner in vitro.
A. Real-time PCR. B. Western blots. Results show that addition of AA induces Smad7 mRNA and protein expression in a time (at a dose of 20 uM) and dosage (3 h for mRNA and 24 h for protein)-dependent manner. Data represent mean ± SEM for at least 3 independent experiments. *p<0.05, **p<0.01, ***p<0.001 versus medium control.