Zfp296 Is a Novel, Pluripotent-Specific Reprogramming Factor (original) (raw)
Figure 3
Pluripotency of iPSCs induced with OSKM+Zfp296.
An iPSC line induced with OSKM+Zfp296 is shown in phase (A), DAPI (B), Oct4 immunostained (C), or Oct4-GFP (D). Teratomas formed with this iPSC line were composed of cartilage (mesoderm; E), neural rosettes (ectoderm; F), and epithelia (endoderm; G). A chimera formed with this iPSC line is shown (H), and offspring from this chimera carried the GFP transgene, which originated from the iPSCs (I).