Do Anti-Angiogenic VEGF (VEGFxxxb) Isoforms Exist? A Cautionary Tale (original) (raw)
Figure 1
Murine VEGF-A splice variants.
Several splice variants of VEGF are produced, by alternative splicing of exons 6 & 7. Exons 3 & 4 encode dimerisation and VEGF receptor binding sites, exon 7 encodes neuropilin binding sites and exons 6 & 7 encode heparin binding sites.