Expression of TRPC6 in Renal Cortex and Hippocampus of Mouse during Postnatal Development (original) (raw)
Figure 1
Localization of TRPC6 in mouse renal cortex during postnatal development.
Immunohistochemical staining of TRPC6 showed the expression of TRPC6 in the mouse renal cortex at P1 (B), P3 (C), P5 (D), P7 (E), P14 (F), P21 (G), P28 (H), and P49 (I). The negative control image was from the renal cortex, in which the primary antibody was a species-appropriate IgG (A). The corresponding linear diagram of relative fluorescent intensity in glomeruli was shown in (J). The sections from P1 to P5 showed that TRPC6 mostly expressed in comma-shaped body, S-shaped body and renal corpuscles of stage III (B-D). After P7 the expression was found in renal corpuscles and it was weakly positive (E-F). During the development, tubules were all observed. Scale bar, 100 µm. Data were presented as means±S.D. n = 6/group. *P<0.05, **P<0.01 vs. adjacent age group.