On the Origin of Tremor in Parkinson’s Disease (original) (raw)
Figure 4
Tremulous activity with variation of dopaminergic parameters.
The parameters _s_1 and _s_2 run along vertical and horizontal axis respectively, color codes for the value of SNR. The point (1, 1) corresponds to the bursting mode shown in Figure 2B. A), B), C), and D) represent SNR1, 2, 3, and 4 respectively. Parameters _s_1 and _s_2 are proxies of dopaminergic status and their higher values correspond to stronger dopamine influence. Thus upper right corner corresponds to a “normal” state of the network, while lower left corner corresponds to a “parkinsonian” state. Blue color indicates the absence of tremor-band oscillations, red color indicates prominent oscillations. Yellow and green correspond to SNR values termed to be tremulous in [48].