On the Origin of Tremor in Parkinson’s Disease (original) (raw)
Figure 5
Tremulous activity with variation of current conductances.
The shades of gray code for the value of SNR1 (like the color code in Figure 4) so that lighter areas exhibit stronger tremor oscillations. A) Bursting activity with variation of the dopaminergic parameter _s_1 and the AHP current conductance gAHP. B) Bursting activity with variation of the dopaminergic parameter _s_1 and the Ca current conductance _g_Ca. Parameters are the same as in Figure 2B. _g_AHP and _g_Ca are in units of the AHP current and the Ca current conductances in Parkinsonian state respectively (_g_AHP = 8.46, _g_Ca = 0.5). Lower values of AHP and Ca currents conductances lead to disappearance of tremor.