A Novel Five Gene Signature Derived from Stem-Like Side Population Cells Predicts Overall and Recurrence-Free Survival in NSCLC (original) (raw)
Figure 3
Heat map showing the expression pattern of 64 genes in lung adenocarcinoma.
Differentially expressed genes in SP vs. MP cells in 4 NSCLC cell lines. A total of 64 genes (58 upregulated and 6 downregulated) with expression levels that showed at least two fold difference across 4 cell lines were selected for hierarchical clustering analysis. Two clusters shown here represent downregulated (I) and upregulated genes (II). The 5 genes that predicted significant prognosis are marked in the map by numbers. The color in red or green reflects relative high or low expression levels, respectively as indicated in the scale bar (log2 transformed scale).