Searching for Lower Female Genital Tract Soluble and Cellular Biomarkers: Defining Levels and Predictors in a Cohort of Healthy Caucasian Women (original) (raw)
Figure 3
Case profiles of longitudinal trends of selected bacterial species counts and soluble biomarkers for women with intermediate Nugent scores on visit 4.
Two women with intermediate Nugent scores on their fourth visits to the clinic (participants 21 and 33) had unique expression profiles of specific soluble markers and bacterial species colonization. Specifically, IL-1β, IL-8 and modestly IL-12(p70) and MIP-1β expression in these women peaked at visit 4. Interestingly, visit 4 was also the time point at which A. vaginae and L. iners peaked for participant 21 and G. vaginalis and L. iners peaked for participant 33. Of note, IL-6 expression dipped in participant 21 but peaked in participant 33 at visit four.