MiR-214 Targets β-Catenin Pathway to Suppress Invasion, Stem-Like Traits and Recurrence of Human Hepatocellular Carcinoma (original) (raw)
Figure 6
Further silencing of miR-214 in HLE cells with miRZip-214 increases EpCAM+ stem-like cell population by activating the β-catenin pathway.
(A) Further silencing of miR-214 in HLE cells with miRZip-214. (B) Silencing miR-214 following transfection with miRZip-214 increased EZH2 and β-catenin expression. (C) Overexpression of EZH2 with pLVTHM-EZH2 activated β-catenin expression. (D) Flow cytometric analysis of EpCAM+ stem-like HLE cells following the silencing of miR-214 (i) and overexpression of EZH2 (ii).